Table 1.
Alcohol | Control | P value | |
---|---|---|---|
|
|||
Number of subjects | 18 | 19 | |
Age (years) | 44 ± 10 | 40 ± 8 | 0.251 |
Body mass index (kg/m2) | 27 ± 4 | 28 ± 5 | 0.738 |
Tobacco smokers/non-smokers (N) | 11/7 | 2/17 | 0.001 |
Amount of alcohol use (drinks/day, TLFB) | 18 ± 6 | <1 | <0.001 |
Alcohol Dependence Severity (ADS) | 20 ± 6 | <1 | <0.001 |
Baseline craving (PACS) | 12 ± 8 | 1 ± 2 | <0.001 |
Baseline peak withdrawal (CIWA) | 9 ± 5 | N.A. | N.A. |
Injected activity of [18F]FMPEP-d2 (MBq) | 187 ± 10 | 181 ± 12 | 0.103 |
Injected amount of [18F]FMPEP-d2 (nmol) | 1.7 ± 0.9 | 1.9 ± 0.8 | 0.547 |
Fraction of free [18F]FMPEP-d2 in plasma (%) | 0.38 ± 0.1 | 0.39 ± 0.2 | 0.886 |
Values are number, mean ± standard deviation, or range. N.A., not applicable.