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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Cancer Res. 2013 Feb 22;73(5):1547–1558. doi: 10.1158/0008-5472.CAN-12-3343

Figure 5.

Figure 5

Local immuno-liposome therapy elicits systemic immunity that inhibits simultaneously established distal tumors. Mice (n=9–10) were inoculated s.c. with B16F10 tumors on both hind flanks simultaneously, then treated i.t. on one flank with PBS or Lip-αCD137+Lip-IL-2Fc on days 9/12/16 (arrows). A. Average growths of treated tumors and contralateral untreated tumors. *p=0.002, **p=0.009, ***p<0.0001. B. Individual growth curves of contralateral untreated tumors in i.t. PBS-treated or immuno-liposome-treated mice. Boxed numbers indicate fraction of long-term cures.