Table 2.
Overall (n = 224) | Fluconazole (n = 127) | Echinocandin (n = 97) | P | |
---|---|---|---|---|
Complete response | ||||
day 7, n (%) | 81 (36) | 47 (37) | 34 (35) | 0.763 |
day 14, n (%)a | 108 (48) | 58 (46) | 50 (52) | 0.383 |
day 28, n (%) | 110 (49) | 65 (51) | 45 (46) | 0.477 |
Survival | ||||
day 7, n (%) | 217 (97) | 121 (95) | 96 (99) | 0.115 |
day 14, n (%) | 205 (92) | 115 (91) | 90 (93) | 0.552 |
day 28, n (%) | 176 (79) | 100 (79) | 76 (78) | 0.944 |
12 weeks, n (%) | 146 (65) | 87 (69) | 59 (61) | 0.232 |
Microbiological success | ||||
day 7, n (%) | 154 (69) | 83 (65) | 71 (73) | 0.210 |
day 14, n (%) | 177 (79) | 100 (79) | 77 (79) | 0.907 |
day 28, n (%) | 182 (81) | 105 (83) | 77 (79) | 0.531 |
Clinical success | ||||
day 7, n (%) | 115 (51) | 67 (53) | 48 (50) | 0.627 |
day 14, n (%) | 135 (60) | 73 (58) | 62 (64) | 0.329 |
day 28, n (%) | 118 (53) | 70 (55) | 48 (50) | 0.403 |
aPrimary outcome.