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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Int J Geriatr Psychiatry. 2012 Nov 5;28(8):858–867. doi: 10.1002/gps.3898

Table 2.

Functionally connected clusters as indicated by a seed region of interest (ROI) prescribed in the posterior cingulate cortex and covarying for the effects of total gray matter volume. Seed ROI MNI coordinates: x=0, y=53, z=−26; radius= 4mm. Adjusted for total gray matter volume. False Discovery Rate (FDR) controlled at 5%. Cluster size > 5 voxels. p-value < 0.001.

Pain Region Cluster Size (# voxels) Maximum Intensity Voxel coordinates t-value
Pain
Widespread Frontal, Temporal, Parietal, and Cerebellar 5758 0 −54 27 61.3778
Widespread Frontal, Temporal, Parietal, and Cerebellar 3024 0 60 0 12.1484
L Middle Temporal Gyrus 352 −60 −9 −21 8.8546
R Cerebellum 163 6 −54 −45 8.4453
L Middle Temporal Gyrus 245 63 −6 −21 7.4509
R Cerebellum 142 30 −75 −36 6.0997
L Cerebellum 100 −27 −81 −39 5.6949
L Hippocampus 13 −27 −18 −21 4.4624
R Insula 8 39 −18 15 4.1594
R Middle Temporal Gyrus 13 60 −36 −9 4.1523
R Middle Frontal Gyrus 11 39 24 21 4.1041
L Fusiform 10 −27 −33 −21 4.0631
L Inferior Frontal Gyrus 6 −48 21 6 4.0174
R Superior Temporal Gyrus 11 45 15 −36 3.8656
L Superior Frontal Gyrus 5 −9 33 54 3.7247
L Caudate 5 −18 18 −3 3.619
No Pain
Widespread Frontal, Temporal, Parietal, and Cerebellar 5510 0 −54 27 64.1825
Widespread Frontal, Temporal, Parietal, and Cerebellar 3693 3 51 6 12.4576
L Middle Temporal Gyrus 398 −60 −12 −18 10.4737
R Middle Temporal Gyrus 313 63 −6 −21 8.9566
R Cerebellum 115 6 −54 −42 6.6093
R Cerebellum 201 27 −81 −33 6.3507
L Cerebellum 75 −27 −84 −42 5.6873
R Caudate 29 15 0 15 4.8097
R Caudate 42 9 6 −3 4.2691
L Middle Frontal Gyrus 12 −39 57 −12 4.0627
L Inferior Frontal Gyrus 7 −54 24 6 3.6571
L Cerebellum 12 −18 −30 −24 3.5511