Table 5.

Results of voxel-wise, within-group analysis of z-transformed functional connectivity values and number of reported painful joints while accounting for the effects of age, education, gender, and total gray matter volume. To control for multiple comparisons and spurious findings, we utilized the following: Cluster size > 5 voxels. p-value < 0.001.

Association with Number of Joints	Region	Cluster size (#voxels)	Maximum Intensity Voxel coordinates			t-value
Direct	L middle temporal	11	−45	−39	−9	4.7347
Direct	R middle temporal	16	60	−36	−6	4.0782
Direct	L middle occipital	5	−24	−96	3	4.0882
Direct	L superior temporal	11	−36	−54	15	4.2537
Inverse	Bilateral middle cingulate	10	0	−21	39	−3.9534
Inverse	R precuneus	13	15	−39	42	−4.4254
Inverse	L inferior parietal	7	−36	−48	48	−3.8474