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. Author manuscript; available in PMC: 2013 Mar 12.
Published in final edited form as: Biol Chem. 2012 Dec 1;393(12):1485–1512. doi: 10.1515/hsz-2012-0198

Figure 6. Hypothetical presentation of electronic energy utilization between mitochondria having mtDNA haplotypes representing Northern or Sub-Saharan origins in terms of latitude.

Figure 6

Under conditions of high energy (ATP) demand, differences in energy utilization exist between mitochondria having different mtDNAs that manifest in differences in electrons used to generate ATP, oxidants and heat as illustrated by the arrows and pie charts. Under conditions of low energy (ATP) demand and excessive caloric intake (*), these profiles shift to decreased use of electronic energy for ATP generation and greater production of oxidants, with those mitochondria having sub-Saharan latitude mtDNAs generating more oxidants compared with those with Northern latitude mtDNAs as indicated by the arrows and pie charts.