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Lack of DJ-1 significantly suppresses the activation of Fyn, and partially so Syk. Lyn (A), Fyn (B), Fgr (C) and Syk (D) were immunoprecipitated from 1 mg protein of whole cell lysates in wild type or DJ-1 KO BMMCs. The activities of immunoprecipitates were measured by ELISA-based Tyrosine Kinase Assay Kit. All values are the means ± SEM from three independent experiments: * P < 0.05 (compared with wild type BMMCs).
