Table 1.
Summary of Cre transgenic Crryflox/flox mouse strains described in the text
| Strain Name | Crry deletion | DAF deletion | Plasma AP complement | Phenotype |
|---|---|---|---|---|
| Tie-2-Cre+ -Crryflox/flox | endothelial cells, blood cells | global | low | not apparent |
| Tie-2-Cre+ -Crryflox/Δ | endothelial cells, blood cells | global | low | not apparent |
| Tie-2-Cre− -CrryΔ/Δ | global | global | low | not apparent |
| Tie-2-Cre− -Crryflox/Δ | - | global | slightly lower | normal |
| Pf4-Cre+ -Crryflox/flox | Platelets | global | normal | increased thrombopoiesis |
| Pf4-Cre− -Crryflox/flox | - | global | normal | normal |