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. Author manuscript; available in PMC: 2014 Oct 9.
Published in final edited form as: J Mol Biol. 2012 Nov 23;425(19):3723–3730. doi: 10.1016/j.jmb.2012.11.024

Table 1.

LncRNAs controlling gene expression post-transcriptionally. Listed are the post-transcriptional processes affected by lncRNAs (column 1), the lncRNAs reported in each regulatory process (column 2), the target molecules (RNAs and proteins) through which the lncRNAs elicit a post-transcriptional influence (column 3), and additional details of the post-transcriptional consequences of lncRNA activity.

Post-transcriptional
processes
LncRNA Target Comments References
Splicing MALAT1 Pre-mRNAs regulated by SR proteins Modulation of splicing patterns [17]
sno-lncRNAs Pre-mRNAs regulated by Fox proteins Modulation of splicing patterns [30]

mRNA Turnover ½-sbsRNAs mRNAs bearing Alu sequences, Staufen-1 targets Increase in mRNA decay [18]
BACE1-AS BACE1 mRNA Increase in mRNA stabilization [19]

Translation lincRNA-p21 JUNB and CTNNB mRNAs Inhibition translation (specific mRNAs) [21]
AS Uchl1 Uchl1 mRNA Promotion of translation (specific mRNA) [36]
BC1 eIF4A and PABP Modulation of translation (global) [20]

miRNA Function Linc-MD1 Decoy for miR-133 and miR-135 Increased translation of MAML1 and MEF2C mRNAs [38]
H19 Gives rise to miR-675 Decreased expression of IGF1R mRNA (miR-675 target) [40]
BACE1-AS BACE1 mRNA Competition with miR-485-5p for binding to BACE1 mRNA [34]