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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Invest Dermatol. 2012 Nov 29;133(4):890–898. doi: 10.1038/jid.2012.407

Fig. 1.

Fig. 1

Gpr177 is expressed in hair follicle development. Immunostaining of the E11.5 (a) and E13.5 (b) skins shows the expression of Gpr177 in the epithelium and underlying mesenchyme. A restricted elevation is found in the epidermal basal cells and hair follicular cells at E15.5 (c) and E17.5 (d), respectively. The inset shows non-uniform expression of Gpr177 in the hair follicle (d). Double labeling of Gpr177 (e-l) with AE3, a marker for the entire epidermis (e, g, i, k), or K14, a marker for the epidermal basal layer (f, h, j, l), identifies the Gpr177-expressing cells at E14.5 (e-f, i-j) and E17.5 (g-h, k-l). Scale bars, 50 μm (a-l).