Fig. 4. Effect of Pol2-M644L and Top1-T722A expression on 2-bp deletions under high-transcription conditions.
A. Effect of Pol2-M644L on 2-bp deletion rates in an rnh201Δ background (Table S2). B. Effect of Top1-T722A expression on 2-bp deletion frequencies in top1Δ rnh201Δ backgrounds (Table S3). Frequencies observed with an empty vector control or WT Top1 expression also are shown. Error bars represent 95% confidence intervals of rates (A) and median frequencies (B).