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Effect of apelin on the saturation binding of [125I]-Tyr4-Ang II to membranes from cells expressing AT1 with APJ
| Apelin (nM) | Ang II Bmax (fmol mg protein−1) |
|---|---|
| 0 | 2004 ± 131.2 |
| 10 | 1286 ± 213.1 |
| 100 | 834.7 ± 312.6 |
| 1000 | 373.1 ± 71.22 |
Calculated Bmax values obtained from saturation isotherm [125I]-Tyr4-Ang II in the presence or absence of various concentration of Ap13. The values represent the mean ± SEM of at least three independent experiments.
