Table 4.
Correlates of Incident Hypertension During Examination Cycle 8
| Predictor Variables During Examination Cycle 7 | Odds Ratio (95% CI) | P Value |
|---|---|---|
| Tonometry modela | ||
| Systolic blood pressure | 3.3 (2.3–4.7) | <.001 |
|
| ||
| Diastolic blood pressure | 1.5 (1.1–1.9) | .004 |
|
| ||
| Forward wave amplitude | 1.6 (1.3–2.0) | <.001 |
|
| ||
| Augmentation index | 1.7 (1.4–2.0) | <.001 |
|
| ||
| CFPWV | 1.3 (1.0–1.6) | .04 |
|
| ||
| Brachial artery modelb | ||
| Flow-mediated dilation | 0.80 (0.67–0.96) | .01 |
|
| ||
| Baseline brachial artery flow | 1.23 (1.04–1.46) | .01 |
Abbreviation: CFPWV, carotid-femoral pulse wave velocity.
Odds ratios per 1-SD difference derived from a single multivariable model in 1048 participants free of hypertension during examination cycle 7 (338 incident cases of hypertension,32%);model was further adjusted for age, sex, body mass index (calculated as weight in kilograms divided by height in meters squared), height, and triglycerides.
Odds ratios per 1-SD difference derived from a single multivariable model in 957 participants free of hypertension with complete brachial artery data during examination cycle 7 (316 incident cases of hypertension, 33%); model was further adjusted for age, sex, body mass index, height, triglycerides, systolic and diastolic blood pressure, CFPWV, forward wave amplitude, and augmentation index.