Skip to main content
. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Radiat Res. 2012 Dec 13;179(2):115–124. doi: 10.1667/RR3126.2

FIG. 4.

FIG. 4

The effects of 40 μM WR1065 (WR) exposure and SOD2 siRNA transfection on the adaptive response end points of cell survival as determined by colony forming ability and micronuclei formation. Panels A and B show the survival response of MEF wild-type and TNFR1−R2− cells, respectively. Panels C and D show micronuclei formation as an end point in MEF wild-type and TNFR1−R2− cells, respectively. Experiments were repeated at least three times and error bars represent the SEM. P values were obtained for comparisons between cells exposed to 40 μM WR1065 without or with transfection with NC- and SOD2 siRNA and cells exposed to 2 Gy only. Adaptive responses for cell survival and micronuclei formation were found to be highly significant for both MEF wild-type and TNFR1−R2− cells.