Table 1.
Socio-demographic variables and clinical characteristicsa.
| CONT | AllPtsb | NOMED | QUET | RISP | ANOVA |
|
|---|---|---|---|---|---|---|
| (n=111) | (n=63) | (n=28) | (n=16) | (n=19) | p value | |
| Age, years | 53.7 (9.1) | 53.9 (9.1) | 53.6 (9.7) | 54.8 (7.5) | 53.3 (9.8) | 1.00 |
| Systolic BP, mm Hg | 129 (16.9) | 137 (17.1) | 138.4 (19.9)d | 139.8 (17.6)d | 132.2 (11.3) | 0.01 |
| Diastolic BP, mm Hg | 76.3 (10.3) | 82.1 (17.8) | 81.2 (11.8) | 87.4 (29.4)d,e | 78.4 (7.4) | 0.009 |
| Mean arterial pressure | 93.9 (11.3) | 100.4 (15.6) | 100.3 (14.1) | 104.9 (22.4)d,e | 96.3 (7.3) | 0.003 |
| Body mass index | 26.9 (4.2) | 29.9 (6.0) | 28.6 (6.4) | 31.0 (4.5)d | 30.7 (6.7)d | <0.001 |
| FRS group c | ||||||
| FRS group 1 | 41 (36.9%) | 29 (46%) | 15 (53.6%) | 4 (25%) | 10 (52.6%) | 0.10f |
| FRS group 2 | 39 (35.1%) | 26 (41.3%) | 11 (39.3%) | 8 (50%) | 7 (36.8%) | |
| FRS group 3 | 31 (27.9%) | 8 (12.7%) | 2 (7.1%) | 4 (25%) | 2 | |
| (10.5%) |
CONT: control group; AllPts: all psychiatric patients; NOMED: unmedicated patients;
QUET: patients on quetiapine; RISP: patients on risperidone; BP: blood pressure.
a
Data are means (SD) except Framingham Risk Score (FRS) groups are n (%).
b
This group is not included in the overall or pairwise comparisons.
c
FRS group assigned as follows: group 1 <10%, group 2=10–20%, group 3 >20%.
d
Post hoc tests: Significantly higher than CONT.
e
Post hoc tests: Significantly higher than RISP.
f
Fisher's exact test.