Figure 1.

Typical DTI workflow. In order to perform a DTI study, researchers need to understand its main application fields, recognize the main artifacts (A) and what acquisition protocols can be used (B). The data should undergo quality control, preprocessing, including format conversion (C), distortions and motion correction (D), and skull stripping (E). Before further analysis, tensors need to be estimated (F) and the resulting data can be visualized as glyphs (G), scalar indices such as colored FA (H), FA (I), and MD (J) or as tractography (K). ROI (L), histogram (M), VBA (N), or TBSS (O) analyses may be performed and the results can be incorporated with fMRI (P) or structural MRI (Q) in multimodal analysis. Finally, results interpretation should be made with extreme caution.