Fig. 6.

Intakes of 0.2% saccharin (US+) and water (US−) during one bottle conditioning phase (A) and preference percentages for CS+ during two-bottle CS+ vs. CS− choice tests in non-deprived or food-deprived OLETF and LETO rats (B). After consuming a fixed 3 ml volume of flavored saccharin (CS), OLETF rats consumed more saccharin (US+) than LETO rats during a 30 min access period across all four days of presentation. Water (US−) intake was not significantly different between strains except on the first day of training (A) (^#P<0.05, ^##P<0.01,^###P<0.001; indicates between strain differences in US intake on conditioning days). When given a 30 min two-bottle choice test between both CS+ and CS− solutions, OLETF rats preferred the CS+ flavor to a greater extent than LETO rats in the non-fasted condition. When food deprived on test, no strain differences were noted in CS+ preference. Both LETO and OLETF rats did not show altered preference for CS+ within strain after overnight food deprivation (B) CS+ preference percentages are given above SEM bars for raw CS (+/−) intakes within each experimental group. (^##P<0.01; indicates between strain preference differences within deprivation condition on test).