Table 1.
Classification of Matrix Metalloproteinases
| Subfamily | MMP | Other Names | MW | Substrates |
| Gelatinases | MMP-2 | Gelatinase A, 72 kDa gelatinase | 73,882 | Col IV, V, VII, X, gelatin, fibronectin, elastine |
| MMP-9 | Gelatinase B, 92 kDa gelatinase | 78,427 | Col IV, V, gelatin | |
| Collagenases | MMP-1 | Interstitial collagenase, fibroblast collagenase | 54,007 | Col I, II, III VII, X, MMP-5, entactin |
| MMP-8 | Neutrophil collagenase, PMNL collagenase | 53,412 | Col I, III | |
| MMP-13 | Collagenase-3 | 53,819 | Col I | |
| Stromelysins | MMP-3 | Stromelysin-1, transin-1 | 53,977 | Col III, IV, IX, X, gelatin, laminin, fibronectin, elastine, casein |
| MMP-7 | PUMP-1, matrilysin | 29,677 | Casein, fibronectin, gelatin | |
| MMP-10 | Stromelysin-2, transin-2 | 54,151 | Col II, IV, V, fibronectin, gelatin | |
| MMP-11 | Stromelysin-3 | 54,595 | Col IV | |
| MMP-12 | Metalloelastase | 54,000 | Elastine, fibronectin | |
| Membrane Bound | MMP-14 | MT1-MMP, MP-X1 | 65,883 | MMP-2 |
| MMP-15 | MT2-MMP | 75,807 | MMP-2 | |
| MMP-16 | MT3-MMP | 69,158 | MMP-2 | |
| MMP-17 | MT4-MMP |
Col, collagen; MMP, matrix metalloproteinases; MT, membrane type; MW, molecular weight; PMNL, polymorphonuclear leucocyte; PUMP, punctuated metalloproteinase.