Table 2.

Statistical Comparison of Values Above Cut-Point, Between Genders Within Respective Line, and Between Wild-Type (Wt) and Transgenic (Tg) Mice Following a Combination Treatment of Recombinant Human FII, FVII, and FX

Group 1	Group 2	p value
FII
Line E Wt female	Line E Tg female	p =0.001
Line H Wt female	Line H Tg female	p = 0.001
FVII
Line E Wt male	Line E Tg male	p = 0.001
Line E Wt female	Line E Tg female	p = 0.001
Line H Wt male	Line H Tg male	p = 0.001
Line H Wt female	Line H Tg female	p = 0.001
Line E Wt male	Line E Wt female	p = 0.01
Line E Tg male	Line E Tg female	p = 0.05
Line H Wt male	Line H Wt female	p = 0.001
FX
Line E Wt female	Line E Tg female	p = 0.01
Line H Wt male	Line H Tg male	p = 0.05
Line H Wt female	Line H Tg female	p = 0.001
Line H Wt male	Line H Wt female	p = 0.05

Log-transformed data were used to calculate significant differences in antidrug-specific Ig concentrations between the different groups using one-way ANOVA.