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. Author manuscript; available in PMC: 2013 Mar 12.
Published in final edited form as: Angiogenesis. 2011 Dec 22;15(1):33–45. doi: 10.1007/s10456-011-9241-1

Fig. 7.

Fig. 7

K562 exosomes induce vascularization of Matrigel plugs in vivo. a Nude mice were injected with Matrigel plugs containing PBS or recombinant IL-8 (positive control), or 100 µg/plug K562 exosomes. Mice were treated with oral administration of dasatinib or imatinib as described in Materials and Methods, and analyzed for plug vascularization after 14 days of treatment. b Plug hemoglobin concentration as a measure of vascularity. Comparison of IL-8 or K562 exosome-containing plugs vs control: * P ≤ 0.01, ** P <0.05