Table 1.
Demographic, neuropsychological, and task-specific performance improvements for the 6 patients who took part in the study. All patients had been diagnosed with amnestic, multidomain MCI prior to taking part in the study; data for the affected non-memory cognitive domain(s) are shown. Some patients were categorized as having relative deficits in non-memory domains (below expectations for that individual but not markedly impaired compared to mean). The Dementia Rating Scale-2 (DRS-2) was administered at the start of the study to grossly re-assess cognitive functioning. Attn = Attention Index; I/P = Initiation/Perseveration Index; Const = Construction Index; Concept = Conceptualization Index; AEMSS = Age and Education Matched Scaled Score; GDS = Geriatric Depression Scale Score. Percent improvement on the trained and untrained lists was calculated by subtracting the pre-training performance from the post-training performance.
| Sex | Age | Educ | Amnestic plus |
Functioning in Non- Memory Domain(s) (in SD) |
DRS-2 Memory (SS) |
DRS-2 Attention (SS) |
DRS-2 I/P (SS) |
DRS-2 Construct (SS) |
DRS-2 Concept (SS) |
DRS-2 AEMSS |
GDS | Trained List Improvement (%) |
Untrained List Improvement (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F | 73 | 15 | Language | −1.6 | 2 | 11 | 12 | 10 | 10 | 5.8 | 3 | 26.7 | 11.1 |
| M | 79 | 14 | Language | −1.2 | 5 | 12 | 3 | 10 | 8 | 3.9 | 1 | 46.7 | 6.7 |
| M | 72 | 16 | Attention (relative) | −0.8 | 6 | 11 | 12 | 10 | 13 | 10 | 0 | 68.9 | 20.0 |
| M | 63 | 16 | Language | −1.7 | 10 | 11 | 11 | 10 | 9 | 8.9 | 4 | 64.4 | 31.1 |
| F | 75 | 15 | Executive (relative) | −0.9 | 10 | 12 | 10 | 10 | 12 | 10.3 | 0 | 60.0 | 28.9 |
| M | 79 | 18 | Executive & Language (relative) |
−1.8 −0.7 |
4 | 10 | 5 | 10 | 9 | 3.8 | 2 | 44.4 | 0 |
| Mean (SD) | 73.5 (5.9) |
15.7 (1.4) |
6.2 (3.3) |
11.17 (.75) |
8.8 (3.9) |
10 (0) |
10.17 (1.9) |
7.1 (3.0) |
2 (1.6) |
51.85 (15.7) |
16.3 (12.5) |