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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Genes Immun. 2012 Nov 15;14(1):13–18. doi: 10.1038/gene.2012.48

Table 1.

SNPs in the ANXA11 region associated with risk of sarcoidosis

SNPd Gened Allelesa AA
 EA
 r2 with
rs1049550
Frequencyb
Control		 Case P-valuec Frequencyb
Control		 Case P-valuec AA EA
rs4399277 A/G 0.09 0.11 0.018 0.07 0.06 0.499 0.03 <0.01
rs2789697 PLAC9 G/C 0.18 0.16 0.007 0.45 0.41 0.102 0.63   0.66
rs3762097 PLAC9 A/C 0.18 0.15 0.002 0.43 0.38 0.069 0.86   0.83
rs2789679 T/A 0.18 0.16 0.004 0.43 0.37 0.039 0.88   0.87
rs1953600 A/G 0.19 0.16 0.002 0.43 0.37 0.028 0.87   0.90
rs79622405 A/G 0.07 0.06 0.041 <0.01 <0.01 — 0.02   —
rs2789686 ANXA11 A/G 0.29 0.31 0.009 0.12 0.15 0.043 0.09   0.10
rs1802932 ANXA11 G/A <0.01 <0.01 — 0.01 0.02 0.046 —   0.01
rs1079242 ANXA11 G/A 0.21 0.18 0.002 0.52 0.45 0.015 0.80   0.62
rs2573346 ANXA11 A/G 0.16 0.14 0.019 0.43 0.37 0.032 0.70   0.90
rs2784773 ANXA11 A/G 0.49 0.50 0.037 0.36 0.41 0.031 0.18   0.37
rs114637323 ANXA11 A/G 0.03 0.04 0.010 <0.01 <0.01 — <0.01   —
rs7067644 ANXA11 G/A 0.43 0.42 0.460 0.61 0.56 0.032 0.33   0.46
rs1049550 ANXA11 C/T 0.17 0.15 0.001 0.42 0.36 0.012 1    1
rs3851054 ANXA11 A/G 0.25 0.23 0.003 0.48 0.43 0.039 0.67   0.80
rs116293236 ANXA11 G/A 0.03 0.04 0.010 <0.01 <0.01 — <0.01   —
rs79199495 ANXA11 A/G 0.05 0.06 0.046 <0.01 <0.01 — 0.01   —
rs7901057 ANXA11 G/A 0.03 0.04 0.024 <0.01 <0.01 — <0.01   —
rs7913325 ANXA11 G/A 0.12 0.13 0.037 0.05 0.07 0.191 0.03   0.04
rs2819947 ANXA11 A/G 0.26 0.24 0.035 0.42 0.36 0.007 0.66    1
rs2819945 ANXA11 G/A 0.35 0.33 0.350 0.56 0.49 0.006 0.45   0.58
rs2573375 ANXA11 C/G 0.18 0.16 0.001 0.42 0.36 0.006 1    1
rs61860052 ANXA11 A/C 0.02 0.01 0.035 0.11 0.09 0.240 <0.01   0.07
rs2253137 G/A 0.21 0.24 0.002 0.17 0.18 0.850 0.07   0.13
rs112535453 A/C 0.11 0.10 0.045 <0.01 <0.01 — 0.12   —

Abbreviations: AA, African American; ANXA11, annexin A11; EA, European American; SNP, single-nucleotide polymorphism.

a

The alleles at each SNP correspond to the minor/major allele among African American sarcoidosis controls.

b

Allele frequencies correspond to the minor allele among African American controls.

c

SNPs with ROADTRIPS allelic association test P-values<0.05.

d

SNPs are listed in ascending order with regard to base pair position in the hg19 build of the human genome. Gene designations were given if the SNP fell within the boundaries 5’ and 3’ boundaries of a gene, as defined by the largest transcript recorded for the gene within the NCBI’s RefSeq database. SNPs without a gene designation are inter-genic.