Table 2.
SNP | Allelesb | ORc | 95% CI | P-value |
---|---|---|---|---|
rs1049550 | C/T | 0.84 | 0.72–0.98 | 0.032 |
rs61860052 | A/C | 0.62 | 0.40–0.97 | 0.038 |
rs4399277 | A/G | 1.31 | 1.06–1.63 | 0.014 |
Abbreviations: ANXA11, annexin A11; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
The resulting multi-SNP model was determined by forward-stepwise selection, after fixing rs1049550 in the model. SNPs were included and retained in the model if the robust Wald statistic P-value was <0.05.
The alleles at each SNP correspond to the minor/major allele among African American sarcoidosis controls.
OR for each SNP with respect to the minor allele.