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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Genes Immun. 2012 Nov 15;14(1):13–18. doi: 10.1038/gene.2012.48

Table 3.

OR estimates for ANXA11 SNPs associateda with sarcoidosis in African Americans, stratified by radiographic evidence of disease ≥ 2 years of follow-up

rs1049550b
rs61860052b
rs4399277b
Radiographic phenotype OR 95% CI P-value OR 95% CI P-value OR 95% CI P-value
Controls 1 Ref Ref 1 Ref Ref 1 Ref Ref
Resolved 0.82 0.64–1.06 0.13 0.66 0.35–1.25 0.20 1.34 0.98–1.84 0.07
Persistent
     All 0.79 0.65–0.95 0.02 0.62 0.34–1.11 0.20 1.32 1.01–1.72 0.04
     Stage IV 0.85 0.62–1.16 0.31 0.39 0.13–1.22 0.11 1.52 1.03–1.22 0.03

Abbreviations: ANXA11, annexin A11; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.

a

SNPs found to be conditionally independent and significantly associated with sarcoidosis (that is, SNPs from Table 2).

b

The additive OR for each SNP correspond to increasing allele count for the C allele for rs1049550, the A allele for rs61860052, and the A allele for rs439927. All ORs were adjusted for sex and percent African ancestry.