Table 3.
rs1049550b |
rs61860052b |
rs4399277b |
|||||||
---|---|---|---|---|---|---|---|---|---|
Radiographic phenotype | OR | 95% CI | P-value | OR | 95% CI | P-value | OR | 95% CI | P-value |
Controls | 1 | Ref | Ref | 1 | Ref | Ref | 1 | Ref | Ref |
Resolved | 0.82 | 0.64–1.06 | 0.13 | 0.66 | 0.35–1.25 | 0.20 | 1.34 | 0.98–1.84 | 0.07 |
Persistent | |||||||||
All | 0.79 | 0.65–0.95 | 0.02 | 0.62 | 0.34–1.11 | 0.20 | 1.32 | 1.01–1.72 | 0.04 |
Stage IV | 0.85 | 0.62–1.16 | 0.31 | 0.39 | 0.13–1.22 | 0.11 | 1.52 | 1.03–1.22 | 0.03 |
Abbreviations: ANXA11, annexin A11; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
SNPs found to be conditionally independent and significantly associated with sarcoidosis (that is, SNPs from Table 2).
The additive OR for each SNP correspond to increasing allele count for the C allele for rs1049550, the A allele for rs61860052, and the A allele for rs439927. All ORs were adjusted for sex and percent African ancestry.