Figure 4.

Temporal dynamics of CS-evoked dopamine and dopamine dependence of conditioned behavior. A, Normalization of conditioned approach behavior and CS-evoked dopamine across all phases of training. B, Conditioned approach behavior on a test session after injection of SCH23390 or saline in animals that received either 5 sessions (saline: n = 6; SCH23390: n = 8; blue) or 15 sessions (saline: n = 7; SCH23390: n = 5; red) of training. Shaded blocks in A correspond to the point in training where pharmacological experiments were conducted in B. The vertical dotted line denotes the decade in training where asymptotic performance was reached. Data are mean ± SEM. *p < 0.05, ***p < 0.005.