Fig. 1.

Chinchillas (n = 2/cohort) were mock infected or challenged with 1 × 10⁸ pfu RSV A2 and nasopharyngeal mucosa was collected 4 days later. Tissues were homogenized and viperin (top panel) or GAPDH (middle panel) was detected by immunoblot. Densitometric analysis of viperin protein abundance is shown and numbers represent the percent increase in viperin expression relative to mock-treated animals normalized to GAPDH expression (bottom panel). Challenge of chinchillas with RSV A2 resulted in increased expression of viperin protein compared to animals that were mock treated.