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. Author manuscript; available in PMC: 2013 May 30.
Published in final edited form as: J Am Chem Soc. 2012 May 18;134(21):8734–8737. doi: 10.1021/ja300218x

Figure 3.

Figure 3

Detailed view of the incoming nucleotide 12b-2, (R)-β,γ-CHF dGTP in the active site of the X-ray crystal structure of its ternary DNA pol β:DNA (PDB ID: 4DO9). The enzyme active site Arg183, Asp190 and Asp192 side chains are shown, along with the nucleotide-binding magnesium and a water molecule. The interatomic distance between the F and Nη2 of Arg183 is 3.11 Å.