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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Paediatr Child Health. 2012 Sep;48(9):794–800. doi: 10.1111/j.1440-1754.2012.02535.x

Figure 2. Development of cortical folding in the premature human brain.

Figure 2

Representative A) 3-dimensional surfaces and B) axial T2-weighted images illustrating regionally-specific cortical folding occurring in the premature brain secondary to sulcation and gyration throughout early development. Provided are images obtained from a single preterm infant from MRI scans performed at 28, 31, 34, and 38 weeks post-mentrual age. Note the marked increase in brain size and folding complexity between each set of images.

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