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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Cancer Prev Res (Phila). 2013 Mar;6(3):177–187. doi: 10.1158/1940-6207.CAPR-12-0414

Figure 3.

Figure 3

Phenotypic characteristics of AL, VF- and CR male mice. A, Body weight, and B, Food intake were monitored weekly throughout the course of the experiment. No significant differences were observed between AL and VF- males, but CR mice weighed less as a result of consuming ~40% fewer calories. Body composition was assessed by qMR at baseline (-1 wk) and at 4-5 wk intervals throughout the study for determination of C, Fat mass and D, Lean mass. CR males had significantly less fat and lean mass, as compared to AL and VF- mice. E, Epididymal and retroperitoneal fat pads were weighed and at 12 wks in study and found to not return in VF- mice, and were also significantly reduced in CR mice, as compared to AL males. F, Insulin sensitivity was measured by ITTs at 3 wks in study. While CR mice were the most insulin sensitive, VF-also tended to improve insulin action in males (P=0.09). Values are means±SE. Different letters denote a significant difference between groups (P<0.05).