Figure 2.

A. Leukocyte accumulation into the mouse peritoneal cavity after injection of BaV. BaV (0.2mg/kg) or sterile saline alone (0.15M NaCl) (control) were injected into the mouse peritoneal cavity in a final volume of 1ml. Total leukocyte, polymorphonuclear (PMN) and mononuclear (MN) cell counts were determined in peritoneal washes harvested 6hr after these injections as described in Materials and Methods. Values represent the mean ±SEM of 5-7 animals. *p<0.05 when compared to control (ANOVA). B. Hemorrhagic effect of BaV. Swiss male mice were injected via i.d. with 50µl of BaV (6.5µg/animal) or pyrogen-free PBS (control animals). After 2hr, the animals were euthanized by cervical dislocation and the skin removed for measuring the hemorrhagic area and tissue hemoglobin concentration. Values represent the mean ±SEM 5-7 animals.*p<0.01 compared to control (ANOVA).