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. 2013 Mar 6;33(10):4561–4569. doi: 10.1523/JNEUROSCI.5525-12.2013

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Copyright © 2013 the authors 0270-6474/13/334561-09$15.00/0

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Figure 1. — Fear extinction memory training and subsequent testing of fear extinction memory. A, Progression of freezing behavior (% of freezing) during fear extinction training. Note, most rats that received foot-shock during fear acquisition (Ext, n = 8; No-ext, n = 8; Failed-ext, n = 6) exhibited high levels of freezing behavior during fear extinction training during the first 10 min, which then gradually declined to the level of the nonshocked control (Control, n = 8) rats. Also, note that some rats that received foot-shock during fear acquisition (NFR, n = 2) did not exhibit any freezing behavior. B, Freezing behavior during fear extinction memory testing. Note the significant variation in freezing among rats that underwent 45 min of fear extinction training (Ext versus Failed-ext). Also note the significantly higher level of freezing in rats that underwent only 15 min of fear extinction training (No-ext) compared with some rats that underwent 45 min of training (Ext). Error bars represent SEM.