Table 1.

Leukocyte surface antigens analyzed with specific monoclonal antibody and the staining of the leukocyte subpopulation

Surface marker	Known or proposed functions
CD11b	Neutrophil and monocyte adhesion to endothelium and extracellular matrix proteins
CD14	Receptor for lipopolysaccharide and its binding protein
CD15	Leukocyte adhesion to endothelial cells; ligand for selectins
CD16	Low affinity receptor for aggregated IgG
CD18	Integrin β2 subunit mediated firm adhesion of leukocyte to endothelium
CD49d	Leukocyte adhesion to extracellular matrix; binds to VCAM-1 and fibronectin
CD62L	L-selectin mediates tethering and rolling of leukocytes
CD64	High affinity receptor for IgG, mediates release of IL-1, IL-6, and TNF-α
CD66b	Role in cell-cell interaction
HLA-DR	Class II major histocompatibility antigen

CD, cluster differentiation; HLA-DR, human leukocyte antigen-DR; IgG, immunoglobulin G; VCAM-1, vascular cell adhesion molecule-1; IL-1/6, interleukin-1/6; TNF-α, tumor necrosis factor-α