Table 3. Unadjusted and adjusted estimates of infectious and non-infectious complications in HIV-infected persons.
Unadjusted | Adjusted | |||
MACS Pre-HAART | OR (95% CI) | p-value | OR (95% CI) | p–value |
Infectious Diagnosis | ||||
Bacterial pneumonia | 21.9 (11.9–40.5) | <0.001 | 21.8 (11.7–40.6) | <0.001 |
Acute sinusitis | 1.39 (1.24–1.55) | <0.001 | 1.64 (1.44–1.86) | <0.001 |
Acute bronchitis | 1.70 (1.46–1.97) | <0.001 | 1.78 (1.48–2.13) | <0.001 |
Any infectious diagnosis | 1.86 (1.71–2.03) | <0.001 | 2.43 (2.20–2.68) | <0.001 |
HR (95% CI) | p–value | HR (95% CI) | p-value | |
Non-Infectious Diagnosis | ||||
Lung Cancer | 1.39 (0.36–5.36) | 0.63 | 1.84* (0.42–8.10) | 0.42 |
COPD | 2.84 (1.06–7.59) | 0.04 | 2.92 (1.02–8.38) | 0.05 |
Any non-infectious diagnosis | 2.09 (0.94–4.64) | 0.07 | 1.95 (0.80–4.74) | 0.14 |
MACS HAART era | OR (95% CI) | p-value | OR (95% CI) | p-value |
Infectious Diagnosis | ||||
Bacterial pneumonia | 3.78 (2.35–6.10) | <0.001 | 4.14 (2.43–7.08) | <0.001 |
Acute sinusitis | 1.59 (1.38–1.83) | <0.001 | 1.46 (1.28–1.68) | <0.001 |
Acute bronchitis | 1.60 (1.32–1.94) | <0.001 | 1.51 (1.24–1.84) | <0.001 |
Any infectious diagnosis | 1.60 (1.43–1.80) | <0.001 | 1.50 (1.34–1.68) | <0.001 |
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Non-Infectious Diagnosis | ||||
Lung Cancer | 3.48 (0.40–30.3) | 0.26 | 2.65* (0.29–24.4) | 0.39 |
COPD | 1.16 (0.29–4.68) | 0.84 | 1.61@ (0.36–7.19) | 0.53 |
Any non-infectious diagnosis | 1.53 (0.48–4.93) | 0.47 | 1.68@ (0.49–5.72) | 0.41 |
WIHS HAART era | OR (95% CI) | p-value | OR (95% CI) | p-value |
Infectious Diagnosis | ||||
Bacterial pneumonia | 13.5 (4.3–42.6) | <0.001 | 9.55 (2.93–31.1) | <0.001 |
Acute sinusitis | 2.27 (1.89–2.73) | <0.001 | 2.17 (1.79–2.63) | <0.001 |
Acute bronchitis | 1.47 (0.83–2.63) | 0.19 | 1.46 (0.79–2.68) | 0.22 |
Any infectious diagnosis | 2.37 (1.97–2.83) | <0.001 | 2.22 (1.84–2.68) | <0.001 |
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Non-Infectious Diagnosis | ||||
Lung Cancer | 1.63 (0.47–5.64) | 0.44 | 2.45 (0.55–10.9) | 0.24 |
Asthma | 0.90 (0.74–1.11) | 0.32 | 1.01 (0.87–1.20) | 0.82 |
Any non-infectious diagnosis | 1.17 (0.85–1.61) | 0.33 | 1.28 (0.88–1.86) | 0.19 |
Adjusted models include the variables age, race, cumulative pack-years smoking, alcohol use, and intravenous drug use unless otherwise noted.
Adjusted for alcohol use, smoke years and age.
@ Excluded IDU due to large missing values.