Skip to main content
. 2013 Mar 12;8(3):e58812. doi: 10.1371/journal.pone.0058812

Table 3. Unadjusted and adjusted estimates of infectious and non-infectious complications in HIV-infected persons.

Unadjusted Adjusted
MACS Pre-HAART OR (95% CI) p-value OR (95% CI) p–value
Infectious Diagnosis
Bacterial pneumonia 21.9 (11.9–40.5) <0.001 21.8 (11.7–40.6) <0.001
Acute sinusitis 1.39 (1.24–1.55) <0.001 1.64 (1.44–1.86) <0.001
Acute bronchitis 1.70 (1.46–1.97) <0.001 1.78 (1.48–2.13) <0.001
Any infectious diagnosis 1.86 (1.71–2.03) <0.001 2.43 (2.20–2.68) <0.001
HR (95% CI) p–value HR (95% CI) p-value
Non-Infectious Diagnosis
Lung Cancer 1.39 (0.36–5.36) 0.63 1.84* (0.42–8.10) 0.42
COPD 2.84 (1.06–7.59) 0.04 2.92 (1.02–8.38) 0.05
Any non-infectious diagnosis 2.09 (0.94–4.64) 0.07 1.95 (0.80–4.74) 0.14
MACS HAART era OR (95% CI) p-value OR (95% CI) p-value
Infectious Diagnosis
Bacterial pneumonia 3.78 (2.35–6.10) <0.001 4.14 (2.43–7.08) <0.001
Acute sinusitis 1.59 (1.38–1.83) <0.001 1.46 (1.28–1.68) <0.001
Acute bronchitis 1.60 (1.32–1.94) <0.001 1.51 (1.24–1.84) <0.001
Any infectious diagnosis 1.60 (1.43–1.80) <0.001 1.50 (1.34–1.68) <0.001
HR (95% CI) p-value HR (95% CI) p-value
Non-Infectious Diagnosis
Lung Cancer 3.48 (0.40–30.3) 0.26 2.65* (0.29–24.4) 0.39
COPD 1.16 (0.29–4.68) 0.84 1.61@ (0.36–7.19) 0.53
Any non-infectious diagnosis 1.53 (0.48–4.93) 0.47 1.68@ (0.49–5.72) 0.41
WIHS HAART era OR (95% CI) p-value OR (95% CI) p-value
Infectious Diagnosis
Bacterial pneumonia 13.5 (4.3–42.6) <0.001 9.55 (2.93–31.1) <0.001
Acute sinusitis 2.27 (1.89–2.73) <0.001 2.17 (1.79–2.63) <0.001
Acute bronchitis 1.47 (0.83–2.63) 0.19 1.46 (0.79–2.68) 0.22
Any infectious diagnosis 2.37 (1.97–2.83) <0.001 2.22 (1.84–2.68) <0.001
HR (95% CI) p-value HR (95% CI) p-value
Non-Infectious Diagnosis
Lung Cancer 1.63 (0.47–5.64) 0.44 2.45 (0.55–10.9) 0.24
Asthma 0.90 (0.74–1.11) 0.32 1.01 (0.87–1.20) 0.82
Any non-infectious diagnosis 1.17 (0.85–1.61) 0.33 1.28 (0.88–1.86) 0.19

Adjusted models include the variables age, race, cumulative pack-years smoking, alcohol use, and intravenous drug use unless otherwise noted.

*

Adjusted for alcohol use, smoke years and age.

@ Excluded IDU due to large missing values.