Table 2. Association of subclinical thyroid status and various cognitive performance tests at baseline.
Thyroid status | p-value for difference | ||||
Cognitive test | Subclinical hyperthyroidism N = 65 | EuthyroidismN = 4,928 | Subclinical hypothyroidism N = 161 | Subclinical hyperthyroidism vs. euthyroidism | Subclinical hypothyroidism vs. euthyroidism |
MMSE, score | 28.04 (0.19) | 28.04 (0.03) | 27.87 (0.12) | 0.97 | 0.15 |
Stroop, seconds | 65.61 (3.07) | 65.34 (0.46) | 65.90 (2.02) | 0.93 | 0.78 |
LDCT, digits coded | 24.31 (0.86) | 23.63 (0.13) | 23.51 (0.54) | 0.42 | 0.79 |
PLTi, pictures remembered | 9.29 (0.23) | 9.45 (0.03) | 9.72 (0.14) | 0.50 | 0.06 |
PLTd, pictures remembered | 10.31 (0.32) | 10.30 (0.05) | 10.65 (0.20) | 0.97 | 0.09 |
Abbreviations: MMSE, Mini-Mental State Examination; LDCT, Letter-Digit Coding Test; PLTi, Picture-Word Learning Test immediate; PLTd, Picture-Word Learning Test delayed. Cognitive tests were presented in mean (standard error). Associations were assessed by linear regression analyses, adjusted for sex, age, education, country, apo E genotype and test version where appropriate.