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. 2013 Mar 12;8(3):e57778. doi: 10.1371/journal.pone.0057778

Table 2. Input parameters and plausible ranges used for sensitivity analysis and relevant references for the Malawi analysis (US $ 2010).

Parameters Base-case References
HIV Epidemiology
1. Number of HIV-infected pregnant women 66,500 (57,000–76,000) [2]
2. Percentage of pregnant women with CD4 count >350 cells/ µL (%) 58 [13]
3. Percentage of pregnant women with CD4 count 349–200 cells/ µL (%) 22 Same as above
4. Percentage of pregnant women with CD4 count <200 cells/ µL (%) 20 Same as above
MTCT transmission rates
5. Background transmission rate without intervention (peripartum)% 22 [17]
6. Monthly post-natal transmission, no prophylaxis, breastfeeding (12 months)% 1.04 [17]
7. Peripartum transmission, Option A % 2.7 [17]
8. Monthly post-natal transmission with infant prophylaxis, breastfeeding (as per Option A)% 0.2 [17]
9. Peripartum transmission, Option B, Option B+ and eligible women on ART % 1.7 [17]
10. Monthly postnatal transmission with ART, breastfeeding (Options B and B+ and women on ART)% 0.2 [17]
Costs
11. HIV Testing and counselling $3.50 MOH Malawi
12. CD4 Screening $20.00 MOH Malawi
13. Follow-up visit/clinical monitoring (per visit) $2.00 MOH Malawi
14. Single-dose NVP $0.20 MOH Malawi
15. AZT (6 months) and AZT+3TC (7 days) $60 MOH Malawi
16. TDF+3TC+EFV (per year) $193.6 MOH Malawi
17. Infant NVP including syringes (per year) $16.00 MOH Malawi
18. Early infant diagnosis $32.50 [35]
19. Cotrimoxazole prophylaxis (per year) $5.00 [36], [37]
21. Discounted lifetime cost for an HIV infected child on ART $ 3195 [39], [40]