Table 3. Igk and Igγ expression in cancers, benign lesions and normal tissues of human breast.
| Factor | Histotype | No. patients | Score, n (%) | ||||
| 0 | 1 | 2 | 3 | 4 | |||
| Igk percentage | ILC | 28 | 0(0) | 0(0) | 3(10.7) | 10(35.7) | 15(53.6) |
| IDC | 127 | 9(7.1) | 27(21.2) | 23(18.1) | 28(22.1) | 40(31.5) | |
| MC | 16 | 1(6.2) | 10(62.5) | 4(25.0) | 1(6.3) | 0(0) | |
| CIS | 15 | 4(26.7) | 6(40) | 4(26.7) | 1(6.7) | 0(0) | |
| BL | 20 | 7(35) | 6(30) | 4(20) | 3(15) | 0(0) | |
| NB | 30 | 5(16.7) | 19(63.3) | 5(16.7) | 1(3.3) | 0(0) | |
| Igγ percentage | ILC | 28 | 1(3.6) | 0(0) | 3(10.7) | 10(35.7) | 14(50.0) |
| IDC | 127 | 12(9.4) | 28(22.1) | 30(23.6) | 23(18.1) | 34(26.8) | |
| MC | 16 | 1(6.2) | 9(56.3) | 5(31.3) | 1(6.2) | 0(0) | |
| CIS | 15 | 3(20.0) | 10(66.7) | 1(6.7) | 1(6.7) | 0(0) | |
| BL | 20 | 7(35.0) | 7(35.0) | 4(20.0) | 2(10.0) | 0(0) | |
| NB | 30 | 7(23.3) | 17(56.7) | 5(16.7) | 1(3.3) | 0(0) | |
| Igk intensity | ILC | 28 | 0(0) | 2(7.1) | 25(89.3) | 1(3.6) | |
| IDC | 127 | 9(7.1) | 43(33.9) | 70(55.1) | 5(3.9) | ||
| MC | 16 | 1(6.2) | 7(43.8) | 8(50.0) | 0(0) | ||
| CIS | 15 | 4(26.7) | 4(26.7) | 7(46.6) | 0(0) | ||
| BL | 20 | 7(35.0) | 11(55.0) | 2(10.0) | 0(0) | ||
| NB | 30 | 5(16.7) | 24(80.0) | 1(3.3) | 0(0) | ||
| Igγ intensity | ILC | 28 | 1(3.6) | 2(7.1) | 24(85.7) | 1(3.6) | |
| IDC | 127 | 12(9.4) | 42(33.1) | 68(53.5) | 5(3.9) | ||
| MC | 16 | 1(6.2) | 6(37.5) | 9(56.3) | 0(0) | ||
| CIS | 15 | 3(20.0) | 5(33.3) | 7(46.7) | 0(0) | ||
| BL | 20 | 7(35.0) | 10(50.0) | 3(15.0) | 0(0) | ||
| NB | 30 | 7(23.3) | 22(73.4) | 1(3.3) | 0(0) | ||
NOTE: Percentage scores of Igκ and Igγ (based on the percentage of tumor cells stained in the sample): 0 = none, 1 = <10%, 2 = 10 to 25%, 3 = 25 to 50%, 4 = >50%. The staining intensity scores of Igκ and Igγ (according to positive cytoplastic signals): 0 = none, 1 = weak, 2 = moderate, 3 = strong.
Abbreviations: IHC, immunohistochemistry; ILC, infiltrating lobular carcinoma; IDC, infiltrating ductal carcinoma; MC, medullary carcinoma; CIS, carcinoma in situ; BL, benign lesions of breast; NB, normal breast tissues.