Table 1. Radiosensitivity of hematopoietic myeloid progenitor cells.
CFU-GM | BFU-E | CFU-Mix | Total CFC | ||
X-rays | D0 | 1.15±0.05a,b | 0.83±0.04c | 0.71±0.06d | 1.07±0.09 |
n | 1.46±0.20 | 7.72±1.00e,f,g | 1.88±0.58 | 1.85±0.33 | |
Carbon-ion beams | D0 | 0.57±0.02h | 0.73±0.03i | 0.64±0.05 | 0.65±0.03j |
n | 1.37±0.28 | 1.00±0.26k | 1.00±0.16 | 1.10±0.11l | |
RBE10% | 2.07 | 2.12 | 1.31 | 1.94 |
Values are the mean±SE. of 6–8 separate experiments. P values were calculated using two-factor factorial ANOVA and Tukey–Kramer test. A significant difference was observed between D0 and n for radiation types (D0: P = 1.40×10−9, n: P = 1.16×10−7) and for each progenitor (D0: P = 1.75×10−3, n: P = 4.53×10−8). aP = 4.97×10−2 vs. BFU-E, bP = 1.33×10−4 vs. CFU-Mix, cP = 6.55×10−3 vs. CFU-Mix, dP = 9.49×10−4 vs. CFC, eP = 2.87×10−3 vs. CFU-GM, fP = 4.01×10−2 vs. CFU-Mix, gP = 4.64×10−3 vs. CFC in X-rays. hP = 3.79×10−6, iP = 0.00196, jP = 6.51×10−5, kP = 2.34×10−3, lP = 2.50×10−2 compared with X-rays.