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. 2013 Mar 12;8(3):e59321. doi: 10.1371/journal.pone.0059321

Table 3. Evaluation of potentially useful markers of 90-day mortality after discharge.

AUC (95% CI) P Cutt-off Sensibility Specificity PPVa NPVb LR+c LR−d DORe Accuracy
CRPf at admission 0.590 (0.511–0.670) 0.024 196 52 67 31 83 1.58 0.72 2.20 64
Albumin at admission 0.621 (0.545–0.697) 0.001 25 65 51 29 83 1.33 0.69 1.93 54
CRPf/albumin at admission 0.612 (0.534–0.689) 0.005 8.7 54 66 31 83 1.59 0.70 2.28 63
CRPf at discharge 0.597 (0.517–0.678) 0.022 50 68 55 31 85 1.51 0.58 2.60 58
Albumin at discharge 0.647 (0.572–0.722) <0.001 25 65 51 29 83 1.33 0.54 2.79 55
CRPf/albumin at discharge 0.619 (0.540–0.698) 0.005 2 72 52 31 86 1.50 0.54 2.79 57

a – PPV  =  positive predictive value; b – NPV  =  negative predictive value; c- LR+  =  Likelihood ratio for a positive result; d – LR−  =  Likelihood ratio for a negative result; e – DOR  =  diagnostic odds ratio (calculated dividing LR+ by LR-); f – CRP  =  C-reactive protein;

Comparisons between AUCs: CRP/Albumin at admission vs. CRP at admission: p = 0.0455; CRP/Albumin at discharge vs. CRP at discharge: p = 0.0438. For all other comparisons: p = NS.