Table 3. Evaluation of potentially useful markers of 90-day mortality after discharge.
AUC (95% CI) | P | Cutt-off | Sensibility | Specificity | PPVa | NPVb | LR+c | LR−d | DORe | Accuracy | |
CRPf at admission | 0.590 (0.511–0.670) | 0.024 | 196 | 52 | 67 | 31 | 83 | 1.58 | 0.72 | 2.20 | 64 |
Albumin at admission | 0.621 (0.545–0.697) | 0.001 | 25 | 65 | 51 | 29 | 83 | 1.33 | 0.69 | 1.93 | 54 |
CRPf/albumin at admission | 0.612 (0.534–0.689) | 0.005 | 8.7 | 54 | 66 | 31 | 83 | 1.59 | 0.70 | 2.28 | 63 |
CRPf at discharge | 0.597 (0.517–0.678) | 0.022 | 50 | 68 | 55 | 31 | 85 | 1.51 | 0.58 | 2.60 | 58 |
Albumin at discharge | 0.647 (0.572–0.722) | <0.001 | 25 | 65 | 51 | 29 | 83 | 1.33 | 0.54 | 2.79 | 55 |
CRPf/albumin at discharge | 0.619 (0.540–0.698) | 0.005 | 2 | 72 | 52 | 31 | 86 | 1.50 | 0.54 | 2.79 | 57 |
a – PPV = positive predictive value; b – NPV = negative predictive value; c- LR+ = Likelihood ratio for a positive result; d – LR− = Likelihood ratio for a negative result; e – DOR = diagnostic odds ratio (calculated dividing LR+ by LR-); f – CRP = C-reactive protein;
Comparisons between AUCs: CRP/Albumin at admission vs. CRP at admission: p = 0.0455; CRP/Albumin at discharge vs. CRP at discharge: p = 0.0438. For all other comparisons: p = NS.