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. 2013 Mar 12;8(3):e58608. doi: 10.1371/journal.pone.0058608

Table 1. Number and distribution of individuals analyzed for post-diagnostic survival and post-diagnostic recurrence and levels of the cohort factors considered.

Survival Recurrence
Training Set Validation Set Training Set Validation Set
Number Percent Number Percent Number Percent Number Percent
Total 272 146 157 92
N 1 Censored 107 39% 75 51% 31 20% 38 41%
Treatment 2 Chemo 3 253 93% 101 69% 150 96% 67 72%
Chemo_Other 4 14 5% 25 17% 5 3% 18 20%
Other 5 5 2% 20 14% 2 1% 7 8%
Preadjuvant Therapy 6 Yes 21 8% 36 25% 7 4% 25 27%
No 251 92% 110 75% 150 96% 67 73%
Additional Treatment 7 Chemo 3 113 41% 49 34% 106 67% 45 49%
Chemo_Other 4 37 14% 35 24% 34 22% 35 38%
Other 5 122 45% 62 42% 17 11% 12 13%
Tumor Stage 8 I_II 9 12 4% 17 12% 5 3% 9 10%
III 10 239 88% 89 61% 143 91% 59 64%
IV 11 21 8% 40 27% 9 6% 24 26%
Tumor Grade 12 I or II 13 12 4% 45 31% 6 4% 35 38%
Rest 14 260 96% 101 69% 151 96% 57 62%
Tumor Residual Disease 15 0 16 71 26% 52 36% 34 22% 30 33%
1_20 17 167 61% 60 41% 102 65% 40 43%
>20 18 34 13% 34 23% 21 13% 22 24%
Recurrence 19 Yes 157 58% 92 63% 157 100% 92 100%
No 115 42% 54 37% 0 0% 0 0%
1

N: Number of patients;

2

Treatment: Type of treatment received;

3

Chemo: Only chemotherapy;

4

Chemo_Other: Chemotherapy plus another treatment;

5

Other: Any treatment other than chemotherapy;

6

Preadjuvant Therapy: Any treatment that the patient received prior to surgery and sample collection;

7

Additional Treatment: Treatment given after initial first round treatment;

8

Tumor Stage: pathological stage of the tumor in AJCC format (Primary Tumor: T; Stage I: IA; IB; IC; Stage II: IIA; IIB; IIC; Stage III: IIIA; IIIB; IIIC; Stage IV: IV);

9

I_II: Stage I or II ovarian cancer;

10

III: Stage III ovarian cancer;

11

IV: Stage IV ovarian cancer;

12

Tumor Grade: Numeric value used to express the degree of abnormality of cancer cells;

13

I or II: Grade I or II tumor;

14

Rest: Any tumor grades other than I or II;

15

Tumor Residual Disease: Measure of the largest remaining nodule;

16

0: No macroscopic disease;

17

1_20∶1–20 mm;

18

>20: Greater than 20 mm;

19

Recurrence: Return of cancer.