Table 1. Number and distribution of individuals analyzed for post-diagnostic survival and post-diagnostic recurrence and levels of the cohort factors considered.
Survival | Recurrence | ||||||||
Training Set | Validation Set | Training Set | Validation Set | ||||||
Number | Percent | Number | Percent | Number | Percent | Number | Percent | ||
Total | 272 | 146 | 157 | 92 | |||||
N 1 Censored | 107 | 39% | 75 | 51% | 31 | 20% | 38 | 41% | |
Treatment 2 | Chemo 3 | 253 | 93% | 101 | 69% | 150 | 96% | 67 | 72% |
Chemo_Other 4 | 14 | 5% | 25 | 17% | 5 | 3% | 18 | 20% | |
Other 5 | 5 | 2% | 20 | 14% | 2 | 1% | 7 | 8% | |
Preadjuvant Therapy 6 | Yes | 21 | 8% | 36 | 25% | 7 | 4% | 25 | 27% |
No | 251 | 92% | 110 | 75% | 150 | 96% | 67 | 73% | |
Additional Treatment 7 | Chemo 3 | 113 | 41% | 49 | 34% | 106 | 67% | 45 | 49% |
Chemo_Other 4 | 37 | 14% | 35 | 24% | 34 | 22% | 35 | 38% | |
Other 5 | 122 | 45% | 62 | 42% | 17 | 11% | 12 | 13% | |
Tumor Stage 8 | I_II 9 | 12 | 4% | 17 | 12% | 5 | 3% | 9 | 10% |
III 10 | 239 | 88% | 89 | 61% | 143 | 91% | 59 | 64% | |
IV 11 | 21 | 8% | 40 | 27% | 9 | 6% | 24 | 26% | |
Tumor Grade 12 | I or II 13 | 12 | 4% | 45 | 31% | 6 | 4% | 35 | 38% |
Rest 14 | 260 | 96% | 101 | 69% | 151 | 96% | 57 | 62% | |
Tumor Residual Disease 15 | 0 16 | 71 | 26% | 52 | 36% | 34 | 22% | 30 | 33% |
1_20 17 | 167 | 61% | 60 | 41% | 102 | 65% | 40 | 43% | |
>20 18 | 34 | 13% | 34 | 23% | 21 | 13% | 22 | 24% | |
Recurrence 19 | Yes | 157 | 58% | 92 | 63% | 157 | 100% | 92 | 100% |
No | 115 | 42% | 54 | 37% | 0 | 0% | 0 | 0% |
N: Number of patients;
Treatment: Type of treatment received;
Chemo: Only chemotherapy;
Chemo_Other: Chemotherapy plus another treatment;
Other: Any treatment other than chemotherapy;
Preadjuvant Therapy: Any treatment that the patient received prior to surgery and sample collection;
Additional Treatment: Treatment given after initial first round treatment;
Tumor Stage: pathological stage of the tumor in AJCC format (Primary Tumor: T; Stage I: IA; IB; IC; Stage II: IIA; IIB; IIC; Stage III: IIIA; IIIB; IIIC; Stage IV: IV);
I_II: Stage I or II ovarian cancer;
III: Stage III ovarian cancer;
IV: Stage IV ovarian cancer;
Tumor Grade: Numeric value used to express the degree of abnormality of cancer cells;
I or II: Grade I or II tumor;
Rest: Any tumor grades other than I or II;
Tumor Residual Disease: Measure of the largest remaining nodule;
0: No macroscopic disease;
1_20∶1–20 mm;
>20: Greater than 20 mm;
Recurrence: Return of cancer.