Figure 3. Knockdown of CDH17 inhibited tumor growth and the expressions of NF-κB, MMP-9 and VEGF in tumor tissue. (A) Upon the termination, masses with fluorescence were larger in mock and miR-neg groups than those in miR-CDH17 group, which was coincident with the gross specimen (B, C). (D) The line chart illustrated that the tumor volume of miR-CDH17 was smaller than the other two groups consecutively, p < 0.05. (E) Expressions of p65 (NFκB), VEGF-C and MMP-9 were all suppressed in tumor tissue of miR-CDH17 nude mice (100μm). There was no significant difference between those in mock group and miR-neg group.