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. Author manuscript; available in PMC: 2014 Feb 15.
Published in final edited form as: Circ Res. 2012 Dec 31;112(4):633–639. doi: 10.1161/CIRCRESAHA.112.275602

Figure 2. Site specific phosphorylation of cMyBP-C in donor and end-stage failing hearts.

Figure 2

Immunoblot analysis of tissue homogenates from donor (n=5), and end-stage failing hearts from patients with idiopathic (IDCM; n=6) or ischemic (ISHD; n=6) cardiomyopathy revealed lower phosphorylation of Ser133 in failing compared to donor hearts. Phosphorylation of previously identified sites, Ser275, Ser284 and Ser304, was also lower. *P<0.01 IDCM and ISHD versus donor in 1-way ANOVA followed by Bonferroni post-hoc test; #P<0.05 ISHD versus IDCM.