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. Author manuscript; available in PMC: 2014 Apr 10.
Published in final edited form as: Chem Rev. 2012 Nov 12;113(4):2584–2667. doi: 10.1021/cr3002142

Figure 70.

Figure 70

Schematic illustration of the principle of flow cytometry for sizing DNA. The sheath flow focuses the sample stream as it flows towards the laser excitation. Dashed lines demarcating the boundary between fluid elements in the sheath flow and the sample flow are included to illustrate the flow focusing concept. The laser induced fluorescence detection is normally performed at a 90° angle with respect to the excitation.