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Four different biological molecules interact with C-terminus of p53. (A) Sirtuin: an NAD-dependent deacetylase (with complex-MoRF), 2H59, (B) cyclin A2 (with ι-MoRF), 1H26, (C) CREB binding protein (with ι-MoRF), 1JSP, and (D) S100 calcium-binding protein (α-MoRF), 1DT7. In the sequence alignments, a residue having a posttranslational modification in PDB is indicated in red. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]
