Table 6.
HLA-DP single amino acid polymorphisms**
| Positions† | Amino acid | Patients (111) n (%) | Controls (91) n (%) | Odds Ratio | Pu value* | Pc value* |
|---|---|---|---|---|---|---|
| 8 | V | 59(53.15) | 39(42.86) | 1.2 | 0.15 | NS |
| 9 | H | 8(7.21) | 11(12.09) | 0.6 | 0.33 | NS |
| 9 | Y | 53(47.75) | 31(34.07) | 1.4 | 0.05 | NS |
| 11 | L | 43(38.74) | 35(38.46) | 1.0 | 0.97 | NS |
| 35 | Y | 27(24.32) | 10(10.99) | 2.2 | 0.01 | NS |
| 36 | A | 85(76.58) | 67(73.63) | 1.0 | 0.63 | NS |
| 36 | V | 78(70.27) | 66(72.53) | 1.0 | 0.72 | NS |
| 55 | A | 86(77.48) | 68(74.73) | 1.0 | 0.65 | NS |
| 55 | D | 75(67.57) | 64(70.33) | 1.0 | 0.67 | NS |
| 56 | A | 88(79.28) | 71(78.02) | 1.0 | 0.83 | NS |
| 56 | E | 75(67.57) | 64(70.33) | 1.0 | 0.67 | NS |
| 57 | D | 36(32.43) | 27(29.67) | 1.1 | 0.67 | NS |
| 65 | L | 41(36.94) | 26(28.57) | 1.3 | 0.21 | NS |
| 69 | E | 44(39.64) | 34(37.36) | 1.1 | 0.74 | NS |
| 76 | V | 45(40.54) | 32(35.16) | 1.2 | 0.43 | NS |
| 84 | D | 60(54.05) | 40(43.96) | 1.2 | 0.15 | NS |
| 84 | G | 97(87.39) | 80(87.91) | 1.0 | 0.91 | NS |
| 85 | E | 60(54.05) | 40(43.96) | 1.2 | 0.15 | NS |
| 85 | G | 99(89.19) | 80(87.91) | 1.0 | 0.78 | NS |
| 86 | A | 60(54.05) | 40(43.96) | 1.2 | 0.15 | NS |
| 86 | P | 99(89.19) | 80(87.91) | 1.0 | 0.78 | NS |
| 87 | M | 99(89.19) | 80(87.91) | 1.0 | 0.78 | NS |
| 87 | V | 60(54.05) | 40(43.96) | 1.2 | 0.15 | NS |
*Pu, uncorrected P values; Pc, corrected P values.
† Polymorphic amino acid positions 8, 9, 11, 33, 35, 36, 55, 56, 57, 65, 69, 76, 84, 85, 86, 87 ** Not displaying amino acid residues that were present in 90% or greater in both patient and control groups, or were present in 10% or fewer in both patient and control groups.