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. 2012 Dec 14;20(4):546–557. doi: 10.1038/cdd.2012.152

Figure 7.

Figure 7

Loss of PIDD does not sensitise stem/progenitor cells to IR. (a) Bone marrow from mice of the indicated genotypes was irradiated with 2 or 4 Gy and 40 000 cells were plated in duplicates in Methylcellulose containing G-CSF or M-CSF. Colonies were scored after 10 days and survival was normalised to untreated controls. Data represent mean±S.E.M.; n=3; *P<0.05 versus wt. (b) Mice of the indicated genotypes were exposed to whole-body IR of 15 Gy and survival was monitored over time. *P<0.05 versus wt (log-rank test)