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. 2013 Mar 13;7:23. doi: 10.3389/fncel.2013.00023

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Copyright © 2013 Song, Volynski, Brenner, Ushkaryov, Walker and Semyanov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Characteristics of the tonic GABA_A current in bafilomycin A1-treated slices. (A) 100 μM picrotoxin (PTX, n = 6) and 25 μM bicuculline (BMI, n = 5) revealed similar tonic GABA_A current in CA1 interneurons of bafilomycin A1-treated slices. (B) Sensitivity of I_hold to exogenous GABA (10 μM) in control (n = 6) and bafilomycin A1-treated slices (n = 7). Black circles—I_hold in control slices, white circles—I_hold in bafilomycin A1-treated slices normalized to corresponding baseline values (dashed line). Gray line—GABA application. N.S. P > 0.05, unpaired t-test.