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. Author manuscript; available in PMC: 2014 Jan 4.
Published in final edited form as: J Chromatogr A. 2012 Nov 19;1271(1):71–85. doi: 10.1016/j.chroma.2012.11.024

Fig. 11.

Fig. 11

pH-zone-refining CCC of D&C Orange No. 5 of three different sample sizes of 350 mg, 1 g and 5 g. The width of pure pH-zone of each component increases nearly proportional to the sample size while the width of the mixing zones remain the same, indicating an important advantage of pH-zone-refining CCC that the increased sample load improves the yield of pure fractions. Experimental conditions are described in Fig. 10 caption.