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Differential activation of ERα and ERβ by select monohydroxylated PAH compounds. (A) Hs578T-ERαLuc and (B) Hs578T-ERβLuc stable cell lines were treated in triplicate with 10µM of PAH compound in the presence or absence of 100nM ICI 182,780 for 24h. Data are expressed as fold induction of raw luciferase units per mg protein over the DMSO control ± SD. Experiments were repeated at least twice. *p < 0.01 compared with DMSO control.
