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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Mol Immunol. 2012 Nov 3;53(4):443–449. doi: 10.1016/j.molimm.2012.10.002

Fig. 3.

Fig. 3

S100A8 significantly reduced oxidative damage in the liver of mice challenged with LPS. (A and C) Immunohistochemistry demonstrated more 8-hydroxydeoxyguanasine (8-OHdG) and nitro tyrosine positive cells in a liver section of LPS treated mice compared to control saline treated mice, an effect mitigated by S100A8. (B and D) Quantification of 8-OHdG and nitro tyrosine positive cells per high power field. Results are mean ± SEM of three independent experiments conducted with 5 mice in each group. The data indicated a statically significant difference when comparing the LPS and LPS/S100A8 groups (*P < 0.01) and the LPS to the control saline treated group (#P < 0.01). Magnification: 200×.